Stellenbezeichnung: Senior Scientist, Imaging Artificial Intelligence (AI) (m,w,d)

Firma: AstraZeneca

Arbeitsort / Location: München, Bayern

Job Beschreibung: Are you ready to apply your research & development skills with AI based solutions for multiplexed tissue imaging; to impact and support AstraZeneca’s drug development and biomarker discovery programmes, in active scientific exchange with the computer vision and AI community? AstraZeneca is a company that always follows the science and turns ideas into life changing medicines. If this sounds like a role you are excited about AstraZeneca might be the one for you!

ABOUT ASTRAZENECA

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious diseases.

SITE DESCRIPTION

Welcome to Computational Pathology Munich, one of over 400 sites here at AstraZeneca, providing a collaborative environment where everyone feels comfortable and able to be themselves. Here’s a sneak peek into what the site offers: after-work events, bright and spacious environment, sustainable office working environment, networking events, family and childcare support and of course the alps around the corner for hiking, biking and skiing.

BUSINESS AREA

Be part of fulfilling our ambition to be world leaders in Oncology. We are already the fastest growing team within AstraZeneca and across the industry, and there are countless new indications and targets in our game-changing pipeline. We deliver this value through launch excellence, commercial effectiveness and maximising the lifecycle. By leveraging our commercialised portfolio, we are confident we can change the practice of medicine and redefine cancer treatment. We’re brave disruptors – entrepreneurial, courageous and pioneering in our approach. Here you have the opportunity to step up, take personal accountability and lead changes in our ever-evolving environment. With pace and drive, comes trust that we will get it done. Embrace the freedom to create and expand your horizons. Always backed and supported by pioneering leaders, this is the place to build a world-class career that’s meaningful and rewarding. Here we’re on a journey to becoming digitally enabled, to discover new ways of offering better solutions to our patients. Join the team with a vision to use data as a tool, to build a better, deeper, more personal understanding of the people we’re helping. To ultimately deliver better outcomes for them – through dynamic omnichannel content, personal relationships and experience.

What you’ll do

Scope of responsibilities include research and development on AI based solutions for multiplexed tissue imaging supporting drug development and biomarker discovery programs, in close collaboration with interfacing functions at global AstraZeneca, in active scientific exchange with the computer vision and AI community.

Generate decisive data based on the whole slide image analysis of multiplexed imaging modalities to advance the Early Oncology drug and biomarker development programs.

Further develop and apply latest artificial intelligence methods to support image and data analysis in Translational Medicine.

Contribute to method and software research and development across multiple functions in the larger organization.

Disseminate knowledge, best practices and developed algorithms and software tools to internal audiences in project meetings, AI seminars, documentation and code libraries, and to the external academic community with conference presentations and journal publications.

Collaborate closely with project stakeholders and interfacing functions such as pathology, quality assurance, data management, software development, data science and bioinformatics.

Comply with the AstraZeneca General Laboratory Standard to support product quality and regulatory compliance in the development, manufacture and distribution of Active Pharmaceutical Ingredients, Medicinal Products and Devices.

Essential for the role

M. Sc., Ph.D. degree in computer sciences, mathematics, physics, bioinformatics or comparable degree, with a focus on computer vision and image-derived data analysis or equivalent

Experience in building and deploying computer vision pipelines, previous experience with (bio-)medical images, especially digital pathology whole slide images, is a strong plus

Experience in at least one aspect of object detection/instance segmentation/panoptic segmentation, self-/weakly-/semi- supervised learning, image-to-image translation or image normalization

Experience in Python. Knowledge of relevant libraries for computer vision (e.g. PyTorch, Keras, TensorFlow, Scikit-Image, openCV etc.) and data analysis (e.g. Pandas, Scikit-Learn, numpy/scipy etc.)

Experience in best practices for software development incl. code formatting, unit testing, version control, experiment tracking, CI pipelines

Track record of scientific publications, conference contributions and/or delivered AI solutions in scientific industry projects in the field of computer vision and/or machine learning for data analysis.

Scientific excellence and passion to work on innovative ways to address image data science challenges in Early Oncology.

Talent to conceptualize, build, communicate and implement novel scientific ideas aligned with the drug development and biomarker strategies.

Keeps pace with the latest advances in the field of image analysis and machine learning

Desirable for the role

Project experience in analyzing multiplexed immunofluorescence images, and correlating image features with response to therapy, using latest deep learning methods (Graph NN, Vision Transformer).

Experience in data analysis and at least one dedicated software environment dedicated to data analysis (Python/pandas, etc.). Knowledge of statistical methods for data analysis (incl. feature selection and survival analysis).

Working in an agile project team using SCRUM or a similar framework.

Competitive salary package and benefits

Close Date: 08/09/2023

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit.

So, what’s next?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

We have one seat available and we hope it’s yours.

Where can I find out more?

Our Social Media,

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Date Posted 11-Aug-2023

Closing Date 07-Sept-2023

AstraZeneca embraces diversity and equality of opportunity. We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills. We believe that the more inclusive we are, the better our work will be. We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics. We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.

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